Yintoni iOsteosarcoma, isifo esiSimilo sikaSushant Singh Rajput eDil Bechara?

Amagama Aphezulu Ebantwaneni

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Itreyila yefilimu ekulindelwe kakhulu kuyo UDil bechara , Umdlali weqonga ongasekhoyo u-Sushant Singh Rajput kunye no-Sanjana Sanghi odlala umdlalo wokuqala bakhululwa ngoMvulo (nge-6 kaJulayi). Isakhiwo sefilimu sijikeleza kuhambo lwabalinganiswa abakhokelayo ababini, uKizie (Sanjana Sanghi), isigulana esinomhlaza kunye noManny (Sushant Singh Rajput), owasinda kwi-osteosarcoma, kunye nendlela amfundisa ngayo ukuba aphile ubomi ngokuzeleyo. Ngokukhawuleza ukuba i-trailer yefilimu iphumile, yafumana iindumiso ezivela kubalandeli kunye nabantu abadumileyo. Nantsi into ekufuneka uyazi malunga ne-osteosarcoma, isifo uSushant Singh Rajput onayo kule filimu.

Yintoni iOsteosarcoma?

I-Osteosarcoma (OS) ekwabizwa ngokuba yi-osteogenic sarcoma lolona hlobo luqhelekileyo lomhlaza wamathambo ochaphazela i-3.4 kwisigidi sabantu kwihlabathi liphela minyaka le. Ngumhlaza wesithathu oqhelekileyo kulutsha. Abantwana abangaphantsi kweminyaka eyi-15 bafumaniswa ukuba bane-osteosarcoma kwaye kunqabile phakathi kwabantwana abangaphantsi kweminyaka emihlanu ubudala. Nangona kunjalo, i-osteosarcoma inokukhula nangaliphi na ixesha [1] .

I-Osteosarcoma ikhula kwiiseli ezenza amathambo. Ihlala ichaphazela amathambo amade afana nalawo afunyanwa ezingalweni nasemilenzeni. I-Osteosarcoma ikakhulu yenzeka kufutshane neziphelo zamathambo amade, anjenge-femur (ithambo lethanga) kufutshane nedolo, i-tibia ehamba phambili (ithambo le-shin) kufutshane nedolo kunye ne-humerus esondeleyo (ithambo lengalo ephezulu) kufutshane negxalaba.

Nangona kunjalo, i-osteosarcoma inokwenzeka nakwezinye iindawo zomzimba ezinjenge-pelvis (ihips), umhlathi kunye namathambo egxalaba aqhelekileyo kubantu abadala abadala [Mbini] , [3] .

Oonobangela beOsteosarcoma

Izizathu ze-osteosarcoma azikacaci nangona kunjalo, izinto ezimbalwa kuthiwa zingunobangela we-osteosarcoma:

• Imfuza -Ukuphazamiseka kwi-p53 kunye ne-Rb (retinoblastoma) yemfuza [4] .

• Ukukhula ngokukhawuleza kwethambo -Umngcipheko we-Osteosarcoma kunye nokukhula kwethambo ngokukhawuleza kunxibelelene. Abantu abancinci abafumana ukukhula ngokukhawuleza bahlala benomngcipheko ophezulu wokukufumana [5] .

• Ukuvezwa kwemitha -Ukuba umntu ukhe wachaphazeleka kwimitha kunyango lolunye uhlobo lomhlaza ngexesha lobuntwana [6] .

Iindidi zeOsteosarcoma

Ngokwe-American Cancer Society, i-osteosarcoma inokuhlelwa ngolu hlobo lulandelayo:

• Ii-osteosarcomas ezikumgangatho ophezulu

• Ii-osteosarcomas ezikumgangatho ophantsi

• I-osteosarcomas ekumgangatho ophakathi [7]

Iimpawu zeOsteosarcoma

• Amathambo okanye iintlungu ezidibeneyo [8] .

• Ukudumba nokubomvu kufutshane nethambo.

• Ithumba elinokuviwa ngesikhumba

• Ngelixa uphakamisa izinto uziva ubuhlungu obugqithisileyo ezingalweni.

• Ukuqhwalela.

• Ithambo elaphukileyo.

Izinto zomngcipheko weOsteosarcoma

• Unyango lwangaphambili lonyango lwemitha [9] .

• Isifo sikaPaget [9] .

• Iimeko ezithile ezizuze ilifa.

Xa ufuna ukubona ugqirha

Ukuba ufumana naziphi na kwezi mpawu zikhankanywe ngasentla, qhagamshelana nogqirha ngokukhawuleza.

Ukuchongwa kweOsteosarcoma

Ugqirha uya kwenza uviwo lomzimba ngokucokisekileyo kwaye abuze malunga neempawu kunye nembali yonyango. Emva koko, ugqirha uya kuqhuba iimvavanyo ezithile zokufumanisa i-osteosarcoma. Olu vavanyo lokuqonda isifo lubandakanya i-X-ray, i-MRI, i-CT scan, i-PET scan, ukuskena kwethambo kunye ne-biopsy [10] .

Unyango lwe-Osteosarcoma

• Ugqirha -Zonke iiseli ezinomhlaza kunye nezinye zeeseli eziphilileyo ezingqonge isuswe kwithambo elichaphazelekayo. Ngamanye amaxesha, utyando lwamalungu okwenziwa kwamalungu omzimba lwenziwa ukususa zonke iiseli ezinomhlaza kunye nezinye iiseli ezisempilweni ngokugcina ilungu liqinile. Ukunqunyulwa kolusu yenye yeenkqubo zotyando ezenziwa ngokususa konke okanye inxenye yengalo okanye umlenze apho iiseli zomhlaza zisasazeke khona. Ilungu lokufakelwa emva koko lifakwa endaweni yelo lungu.

• Unyango ngamayeza -Lunyango olusetyenziselwa ukubulala iiseli zomhlaza ngoncedo lweziyobisi. Okwangoku, i-neoadjuvant chemotherapy yenziwa ngaphambi kotyando nasemva kotyando, i-adjuvant chemotherapy yenziwa.

• Unyango ngemitha - Olu nyango lusebenzisa imitha enamandla amakhulu ukutshabalalisa iiseli zomhlaza. Uphononongo luka-2013 lubonise ukuba ezinye izigulana ezine-osteosarcoma ezifumene i-extracorporeal irradiation (ECI) zibonise ukusebenza ngokuthintela isifo ukuba singaphinde senzeke kwakhona kwaye zehlisa nomngcipheko wosulelo [Shumi elinanye] .

• Unyango lwe-IFN -Yenye inkqubo yonyango lwe-osteosarcoma esebenza ngokucinezela iiseli zethumba [12] .

Ii-FAQ eziqhelekileyo

Q. Ngubani onokufumana i-osteosarcoma?

UKUYA . Abantwana nabakwishumi elivisayo basemngciphekweni omkhulu. Nangona kunjalo, abantu abadala abadala banokuyifumana ukuba banesimo esele sikhona njengesifo sikaPaget okanye babekhe bafumana unyango ngemitha.

Q. Lithini inqanaba lokusinda kwe-osteosarcoma?

UKUYA . Iqondo lokusinda kwe-osteosarcoma lenyuke laya ngaphezulu kweepesenti ze-65. Kodwa, ukuba i-osteosarcoma isasazekile kwimiphunga okanye kwamanye amathambo, inqanaba lokusinda liya kuba sezantsi.

Q. Ziva njani iintlungu ze-osteosarcoma?

UKUYA. Isigulana se-osteosarcoma sinokufumana iintlungu ezibuthathaka kwithambo okanye ngokudibeneyo esijikeleze ithumba.

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